Despite the widespread use of iridium (Ir) in catalytic converters for improved capacity for reducing carbon monoxide (CO), hydrocarbon (HC) and nitrogen oxide (NO(x)) emissions, there is a lack of studies that have assessed possible toxicological hazards of exposure to Ir. The present investigation indicates that female Wistar rats exposed to Ir in the drinking water for 90 days displayed renal toxicity based on the elevated urinary retinol binding protein (RBP) and albumin. The RBP was more sensitive to albumin, showing significant increases at 0.01 mg/L.

The effects of iridium on the renal function of female Wistar rats / Iavicoli, Ivo; Fontana, Luca; Marinaccio, Alessandro; Alimonti, Alessandro; Pino, Anna; Bergamaschi, Antonio; Calabrese, Edward J.. - In: ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY. - ISSN 0147-6513. - 74:7(2011), pp. 1795-1799. [10.1016/j.ecoenv.2011.06.014]

The effects of iridium on the renal function of female Wistar rats

IAVICOLI, Ivo;Fontana, Luca;
2011

Abstract

Despite the widespread use of iridium (Ir) in catalytic converters for improved capacity for reducing carbon monoxide (CO), hydrocarbon (HC) and nitrogen oxide (NO(x)) emissions, there is a lack of studies that have assessed possible toxicological hazards of exposure to Ir. The present investigation indicates that female Wistar rats exposed to Ir in the drinking water for 90 days displayed renal toxicity based on the elevated urinary retinol binding protein (RBP) and albumin. The RBP was more sensitive to albumin, showing significant increases at 0.01 mg/L.
2011
The effects of iridium on the renal function of female Wistar rats / Iavicoli, Ivo; Fontana, Luca; Marinaccio, Alessandro; Alimonti, Alessandro; Pino, Anna; Bergamaschi, Antonio; Calabrese, Edward J.. - In: ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY. - ISSN 0147-6513. - 74:7(2011), pp. 1795-1799. [10.1016/j.ecoenv.2011.06.014]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/616204
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