The complexes (acetylhistamine)2copper+ and (acetyl-L-histidine)2copper+ have been studied in aqueous solutions by means of proton magnetic resonance spectroscopy. The amide group proved to be unable to complex Cu+ both alone and in conjunction with the nonspecific imidazole ligand. The Cu2+ specific carboxylate group, on the other hand, appears to be a possible site of coordination also for Cu+ when coupled with the imidazole ligand. These results are interpreted with respect to the problem of the active site of copper proteins with redox activity.

Model ligands for copper proteins. Proton magnetic resonance study of acetylhistamine and acetylhistidine complexes with copper(I) / Temussi, P. A.; Vitagliano, Aldo. - In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. - ISSN 0002-7863. - STAMPA. - 97:(1975), pp. 1572-1575.

Model ligands for copper proteins. Proton magnetic resonance study of acetylhistamine and acetylhistidine complexes with copper(I)

VITAGLIANO, ALDO
1975

Abstract

The complexes (acetylhistamine)2copper+ and (acetyl-L-histidine)2copper+ have been studied in aqueous solutions by means of proton magnetic resonance spectroscopy. The amide group proved to be unable to complex Cu+ both alone and in conjunction with the nonspecific imidazole ligand. The Cu2+ specific carboxylate group, on the other hand, appears to be a possible site of coordination also for Cu+ when coupled with the imidazole ligand. These results are interpreted with respect to the problem of the active site of copper proteins with redox activity.
1975
Model ligands for copper proteins. Proton magnetic resonance study of acetylhistamine and acetylhistidine complexes with copper(I) / Temussi, P. A.; Vitagliano, Aldo. - In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. - ISSN 0002-7863. - STAMPA. - 97:(1975), pp. 1572-1575.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/489498
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact