The major outer membrane proteins (OMPs) isolated from Pasteurella haemolytica induce alterations of the biological activity of bovine polymorphonuclear leukocytes (PMNs). A dose-dependent reduction of the capacity of adherence to nylon wool in vitro was observed. OMPs also acted as chemotaxins at concentrations between 5 and 20 microg/ml. Concentrations lower than 5 microg/ml did not give considerable results. Preincubation with 5 microg/ml of OMPs led to modifications in the values of the phagocytic index and of intracellular killing, which were found to be diminished with respect to controls.
Effect of Pasteurella haemolytica outer membrane proteins on bovine neutrophils / Iovane, G; Galdiero, M; Vitiello, M; DE MARTINO, Luisa. - In: FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY. - ISSN 0928-8244. - STAMPA. - 20:1(1998), pp. 29-36.
Effect of Pasteurella haemolytica outer membrane proteins on bovine neutrophils.
Vitiello M;DE MARTINO, LUISA
1998
Abstract
The major outer membrane proteins (OMPs) isolated from Pasteurella haemolytica induce alterations of the biological activity of bovine polymorphonuclear leukocytes (PMNs). A dose-dependent reduction of the capacity of adherence to nylon wool in vitro was observed. OMPs also acted as chemotaxins at concentrations between 5 and 20 microg/ml. Concentrations lower than 5 microg/ml did not give considerable results. Preincubation with 5 microg/ml of OMPs led to modifications in the values of the phagocytic index and of intracellular killing, which were found to be diminished with respect to controls.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
