A new type of cytotoxic poly-tetrahydrofuran compound, embodying a novel tricyclic spiroketal moiety, has been obtained through an unprecedented PCC-mediated stereoselective oxidative spiroketalization process.

Discovery of a novel one-step RuO4-catalysed tandem oxidative polycyclization/ double spiroketalization process. Access to a new type of polyether bis-spiroketal compound displaying antitumour activity / Piccialli, Vincenzo; Zaccaria, Sabrina; Borbone, Nicola; Oliviero, Giorgia; D'Errico, Stefano; Hemminki, A.; Cerullo, V.; Romano, V.; Tuzi, Angela; Centore, Roberto. - In: TETRAHEDRON. - ISSN 0040-4020. - STAMPA. - 66:(2010), pp. 9370-9378. [10.1016/j.tet.2010.10.004]

Discovery of a novel one-step RuO4-catalysed tandem oxidative polycyclization/ double spiroketalization process. Access to a new type of polyether bis-spiroketal compound displaying antitumour activity

PICCIALLI, VINCENZO;ZACCARIA, SABRINA;BORBONE, NICOLA;OLIVIERO, GIORGIA;D'ERRICO, STEFANO;CERULLO V.;TUZI, ANGELA;CENTORE, ROBERTO
2010

Abstract

A new type of cytotoxic poly-tetrahydrofuran compound, embodying a novel tricyclic spiroketal moiety, has been obtained through an unprecedented PCC-mediated stereoselective oxidative spiroketalization process.
2010
Discovery of a novel one-step RuO4-catalysed tandem oxidative polycyclization/ double spiroketalization process. Access to a new type of polyether bis-spiroketal compound displaying antitumour activity / Piccialli, Vincenzo; Zaccaria, Sabrina; Borbone, Nicola; Oliviero, Giorgia; D'Errico, Stefano; Hemminki, A.; Cerullo, V.; Romano, V.; Tuzi, Angela; Centore, Roberto. - In: TETRAHEDRON. - ISSN 0040-4020. - STAMPA. - 66:(2010), pp. 9370-9378. [10.1016/j.tet.2010.10.004]
File in questo prodotto:
File Dimensione Formato  
Tetrahedron 2010 Piccialli.pdf

non disponibili

Tipologia: Documento in Post-print
Licenza: Accesso privato/ristretto
Dimensione 609.75 kB
Formato Adobe PDF
609.75 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/373233
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 13
  • ???jsp.display-item.citation.isi??? 12
social impact