The possibility that individual chronic obstructive pulmonary disease (COPD) patients respond better to either tiotropium or salmeterol has been suggested and an acute bronchodilator test might help to guide the choice of therapy. We explored the responses to tiotropium and salmeterol within the first 3 h using the recommended dosages (18 g for tiotropium and 50 g for salmeterol) in order to verify whether there are differences in the short-term bronchodilator effects between these two long-acting bronchodilators in patients with stable COPD. Moreover, we investigated whether these differences could discriminate between the two agents.
An acute bronchodilator test with tiotropium or salmeterol does not allow a subdivision of patients according to responses / Matera, Mg; SANDUZZI ZAMPARELLI, Alessandro; Ponticiello, Antonio; Vatrella, A; Salzillo, A; Cazzola, M.. - In: RESPIRATION. - ISSN 0025-7931. - ELETTRONICO. - 5:(2005), pp. 466-470.
An acute bronchodilator test with tiotropium or salmeterol does not allow a subdivision of patients according to responses
SANDUZZI ZAMPARELLI, ALESSANDRO;PONTICIELLO, ANTONIO;
2005
Abstract
The possibility that individual chronic obstructive pulmonary disease (COPD) patients respond better to either tiotropium or salmeterol has been suggested and an acute bronchodilator test might help to guide the choice of therapy. We explored the responses to tiotropium and salmeterol within the first 3 h using the recommended dosages (18 g for tiotropium and 50 g for salmeterol) in order to verify whether there are differences in the short-term bronchodilator effects between these two long-acting bronchodilators in patients with stable COPD. Moreover, we investigated whether these differences could discriminate between the two agents.File | Dimensione | Formato | |
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