The hitherto unknown 5,6-dihydroxy-3-mercaptoindole (4a) and its 2-carbomethoxy derivative (4b), as well as the analogous 5-hydroxy 3-mercaptoindoles, have been conveniently obtained as O,S-acetyl derivatives 3a-d by thiocyanation of the corresponding acetoxyindoles 1a-d with the NH4SCN/oxone system followed by SMI2 reduction and acetylation
The first entry to 5,6-dihydroxy-3-mercaptoindole, 5-hydroxy-3-mercaptoindole and their 2-carbomethoxy derivatives by a mild thiocyanation/reduction methodology / Pezzella, Alessandro; A., Palma; Iadonisi, Alfonso; Napolitano, Alessandra; D'Ischia, Marco. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - STAMPA. - 48:22(2007), pp. 3883-3886. [10.1016/j.tetlet.2007.03.141]
The first entry to 5,6-dihydroxy-3-mercaptoindole, 5-hydroxy-3-mercaptoindole and their 2-carbomethoxy derivatives by a mild thiocyanation/reduction methodology.
PEZZELLA, ALESSANDRO;IADONISI, ALFONSO;NAPOLITANO, ALESSANDRA;D'ISCHIA, MARCO
2007
Abstract
The hitherto unknown 5,6-dihydroxy-3-mercaptoindole (4a) and its 2-carbomethoxy derivative (4b), as well as the analogous 5-hydroxy 3-mercaptoindoles, have been conveniently obtained as O,S-acetyl derivatives 3a-d by thiocyanation of the corresponding acetoxyindoles 1a-d with the NH4SCN/oxone system followed by SMI2 reduction and acetylationI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
