Four new acyclic diterpene glycosides named capsianosides (1-4), together with 12 known compounds, were isolated from the fresh sweet pepper fruits of Capsicum annuum L., a plant used as a vegetable food, spice, and external medicine. The chemical structures of new natural compounds, as well as their absolute configurations, were established by means of spectroscopic data including infrared, high-resolution mass spectrometry, and one- and two-dimensional nuclear magnetic resonance and by chemical derivatization. The known capsidiol (11) showed bacteriostatic properties in vitro against Helicobacter pylori with a minimum inhibitory concentration (MIC) of 200 microg/mL when compared with the commercial drug metronidazole (MIC, 250 microg/mL). Some purified components were also tested for their antioxidant activities.

New constituents of sweet Capsicum annuum L. fruits and evaluation of their biological activity / DE MARINO, Simona; Borbone, Nicola; F., Gala; Zollo, Franco; G., Fico; R., Pagiotti; M., Iorizzi. - In: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. - ISSN 0021-8561. - STAMPA. - 54:20(2006), pp. 7508-7516. [10.1021/jf061404z]

New constituents of sweet Capsicum annuum L. fruits and evaluation of their biological activity

DE MARINO, SIMONA;BORBONE, NICOLA;ZOLLO, FRANCO;
2006

Abstract

Four new acyclic diterpene glycosides named capsianosides (1-4), together with 12 known compounds, were isolated from the fresh sweet pepper fruits of Capsicum annuum L., a plant used as a vegetable food, spice, and external medicine. The chemical structures of new natural compounds, as well as their absolute configurations, were established by means of spectroscopic data including infrared, high-resolution mass spectrometry, and one- and two-dimensional nuclear magnetic resonance and by chemical derivatization. The known capsidiol (11) showed bacteriostatic properties in vitro against Helicobacter pylori with a minimum inhibitory concentration (MIC) of 200 microg/mL when compared with the commercial drug metronidazole (MIC, 250 microg/mL). Some purified components were also tested for their antioxidant activities.
2006
New constituents of sweet Capsicum annuum L. fruits and evaluation of their biological activity / DE MARINO, Simona; Borbone, Nicola; F., Gala; Zollo, Franco; G., Fico; R., Pagiotti; M., Iorizzi. - In: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. - ISSN 0021-8561. - STAMPA. - 54:20(2006), pp. 7508-7516. [10.1021/jf061404z]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/200974
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