Sfoglia per Autore
D898_E901 RET Deletion Is Oncogenic, Responds to Selpercatinib, and Treatment Resistance Can Arise Via RET-Independent Mechanisms
2023 Porcelli, Tommaso; Moccia, Marialuisa; DE STEFANO, MARIA ANGELA; Ambrosio, Raffaele; Capoluongo, Ettore Domenico; Santoro, Massimo; Hadoux, Julien; Schlumberger, Martin; Carlomagno, Francesca; Salvatore, Domenico
Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose
2022 Zhang, Lingtian; Moccia, Marialuisa; Briggs, David C; Bharate, Jaideep B; Lakkaniga, Naga Rajiv; Knowles, Phillip; Yan, Wei; Tran, Phuc; Kharbanda, Anupreet; Wang, Xiuqi; Leung, Yuet-Kin; Frett, Brendan; Santoro, Massimo; Mcdonald, Neil Q; Carlomagno, Francesca; Li, Hong-Yu
Discovery of pyrazolo-thieno[3,2-d]pyrimidinylamino-phenyl acetamides as type-II pan-tropomyosin receptor kinase (TRK) inhibitors: Design, synthesis, and biological evaluation
2021 Yan, W.; Zhang, L.; Lv, F.; Moccia, M.; Carlomagno, F.; Landry, C.; Santoro, M.; Gosselet, F.; Frett, B.; Li, H. -Y.
Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases
2021 Moccia, M.; Yang, D.; Lakkaniga, N. R.; Frett, B.; Mcconnell, N.; Zhang, L.; Brescia, A.; Federico, G.; Zhang, L.; Salerno, P.; Santoro, M.; Li, H. -Y.; Carlomagno, F.
Bioisosteric discovery of npa101.3, a second-generation ret/vegfr2 inhibitor optimized for single-agent polypharmacology
2020 Moccia, M.; Frett, B.; Zhang, L.; Lakkaniga, N. R.; Briggs, D. C.; Chauhan, R.; Brescia, A.; Federico, G.; Yan, W.; Santoro, M.; Mcdonald, N. Q.; Li, H. -Y.; Carlomagno, F.
Ret gene fusions in malignancies of the thyroid and other tissues
2020 Santoro, M.; Moccia, M.; Federico, G.; Carlomagno, F.
Identification of Novel Small Molecule Inhibitors of Oncogenic RET Kinase
2015 Moccia, Marialuisa; Liu, Qingsong; Guida, Teresa; Federico, Giorgia; Brescia, Annalisa; Zhao, Zheng; Choi, Hwan Geun; Deng, Xianming; Tan, Li; Wang, Jinhua; Billaud, Marc; Gray, Nathanael S; Federico, Giorgia; Santoro, Massimo
Fragment-Based Discovery of a Dual pan-RET/VEGFR2 Kinase Inhibitor Optimized for Single-Agent Polypharmacology
2015 Frett, Brendan; Carlomagno, Francesca; Moccia, Marialuisa; Brescia, Annalisa; Federico, Giorgia; De Falco, Valentina; Admire, Brittany; Chen, Zhongzhu; Qi, Wenqing; Santoro, Massimo; Li, Hong yu
Identification of two novel RET kinase inhibitors through MCR-based drug discovery: design, synthesis and evaluation
2014 Frett, B; Moccia, M; Carlomagno, Francesca; Santoro, Massimo; Li, Hy
| Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|---|
| D898_E901 RET Deletion Is Oncogenic, Responds to Selpercatinib, and Treatment Resistance Can Arise Via RET-Independent Mechanisms | 1.1 Articolo in rivista | 2023 | Porcelli, Tommaso; Moccia, Marialuisa; DE STEFANO, MARIA ANGELA; Ambrosio, Raffaele; Capoluongo, Ettore Domenico; Santoro, Massimo; Hadoux, Julien; Schlumberger, Martin; Carlomagno, Francesca; Salvatore, Domenico | |
| Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose | 1.1 Articolo in rivista | 2022 | Zhang, Lingtian; Moccia, Marialuisa; Briggs, David C; Bharate, Jaideep B; Lakkaniga, Naga Rajiv; Knowles, Phillip; Yan, Wei; Tran, Phuc; Kharbanda, Anupreet; Wang, Xiuqi; Leung, Yuet-Kin; Frett, Brendan; Santoro, Massimo; Mcdonald, Neil Q; Carlomagno, Francesca; Li, Hong-Yu | |
| Discovery of pyrazolo-thieno[3,2-d]pyrimidinylamino-phenyl acetamides as type-II pan-tropomyosin receptor kinase (TRK) inhibitors: Design, synthesis, and biological evaluation | 1.1 Articolo in rivista | 2021 | Yan, W.; Zhang, L.; Lv, F.; Moccia, M.; Carlomagno, F.; Landry, C.; Santoro, M.; Gosselet, F.; Frett, B.; Li, H. -Y. | |
| Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases | 1.1 Articolo in rivista | 2021 | Moccia, M.; Yang, D.; Lakkaniga, N. R.; Frett, B.; Mcconnell, N.; Zhang, L.; Brescia, A.; Federico, G.; Zhang, L.; Salerno, P.; Santoro, M.; Li, H. -Y.; Carlomagno, F. | |
| Bioisosteric discovery of npa101.3, a second-generation ret/vegfr2 inhibitor optimized for single-agent polypharmacology | 1.1 Articolo in rivista | 2020 | Moccia, M.; Frett, B.; Zhang, L.; Lakkaniga, N. R.; Briggs, D. C.; Chauhan, R.; Brescia, A.; Federico, G.; Yan, W.; Santoro, M.; Mcdonald, N. Q.; Li, H. -Y.; Carlomagno, F. | |
| Ret gene fusions in malignancies of the thyroid and other tissues | 1.8 Articolo in rassegna (review) | 2020 | Santoro, M.; Moccia, M.; Federico, G.; Carlomagno, F. | |
| Identification of Novel Small Molecule Inhibitors of Oncogenic RET Kinase | 1.1 Articolo in rivista | 2015 | Moccia, Marialuisa; Liu, Qingsong; Guida, Teresa; Federico, Giorgia; Brescia, Annalisa; Zhao, Zheng; Choi, Hwan Geun; Deng, Xianming; Tan, Li; Wang, Jinhua; Billaud, Marc; Gray, Nathanael S; Federico, Giorgia; Santoro, Massimo | |
| Fragment-Based Discovery of a Dual pan-RET/VEGFR2 Kinase Inhibitor Optimized for Single-Agent Polypharmacology | 1.1 Articolo in rivista | 2015 | Frett, Brendan; Carlomagno, Francesca; Moccia, Marialuisa; Brescia, Annalisa; Federico, Giorgia; De Falco, Valentina; Admire, Brittany; Chen, Zhongzhu; Qi, Wenqing; Santoro, Massimo; Li, Hong yu | |
| Identification of two novel RET kinase inhibitors through MCR-based drug discovery: design, synthesis and evaluation | 1.1 Articolo in rivista | 2014 | Frett, B; Moccia, M; Carlomagno, Francesca; Santoro, Massimo; Li, Hy |
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